Pancreatic-targeted lipid nanoparticles based on organ capsule filtration

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In November, just a few days before Thanksgiving, Anthropic released Claude Opus 4.5 and naturally my coworkers were curious if it was a significant improvement over Sonnet 4.5. It was very suspicious that Anthropic released Opus 4.5 right before a major holiday since companies typically do that in order to bury underwhelming announcements as your prospective users will be too busy gathering with family and friends to notice. Fortunately, I had no friends and no family in San Francisco so I had plenty of bandwidth to test the new Opus.

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Early phys